AAGAB

Protein-coding gene in the species Homo sapiens
AAGAB
Identifiers
AliasesAAGAB, KPPP1, PPKP1, PPKP1A, p34, FLJ11506, alpha- and gamma-adaptin binding protein, alpha and gamma adaptin binding protein
External IDsOMIM: 614888; MGI: 1914189; HomoloGene: 11648; GeneCards: AAGAB; OMA:AAGAB - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for AAGAB
Genomic location for AAGAB
Band15q23Start67,200,667 bp[1]
End67,255,195 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for AAGAB
Genomic location for AAGAB
Band9|9 CStart63,509,942 bp[2]
End63,551,870 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • islet of Langerhans

  • rectum

  • gastrocnemius muscle

  • prefrontal cortex

  • monocyte

  • stromal cell of endometrium

  • secondary oocyte

  • anterior pituitary

  • Achilles tendon

  • body of pancreas
Top expressed in
  • spermatocyte

  • lacrimal gland

  • lens

  • ascending aorta

  • supraoptic nucleus

  • aortic valve

  • saccule

  • neural tube

  • thymus

  • epithelium of stomach
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • cytoplasm
  • cytosol
  • nuclear speck
Biological process
  • protein transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79719

66939

Ensembl

ENSG00000103591

ENSMUSG00000037257

UniProt

Q6PD74

Q8R2R3

RefSeq (mRNA)

NM_001271885
NM_001271886
NM_024666

NM_025857
NM_001357323

RefSeq (protein)

NP_001258814
NP_001258815
NP_078942

NP_080133
NP_001344252

Location (UCSC)Chr 15: 67.2 – 67.26 MbChr 9: 63.51 – 63.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha- and Gamma-Adaptin Binding Protein, also known as AAGAB, is a human gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000103591 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037257 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FLJ11506 hypothetical protein FLJ11506".
  6. ^ Reference GH. "AAGAB gene". Genetics Home Reference. Archived from the original on 2017-12-06. Retrieved 2017-11-24.

Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


  • v
  • t
  • e