Acefurtiamine

Chemical compound
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Identifiers
  • (3E)-4-{[(4-Amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-3-[(furan-2-ylcarbonyl)sulfanyl]pent-3-en-1-yl (acetyloxy)acetate
CAS Number
  • 10072-48-7 ☒N
PubChem CID
  • 3037171
ChemSpider
  • 2300987 checkY
UNII
  • 6APJ3D1308
ChEMBL
  • ChEMBL2104090 ☒N
CompTox Dashboard (EPA)
  • DTXSID20864202 Edit this at Wikidata
Chemical and physical dataFormulaC21H24N4O7SMolar mass476.50 g·mol−13D model (JSmol)
  • Interactive image
  • O=C(OCC(=O)OCCC(\SC(=O)c1occc1)=C(/N(C=O)Cc2cnc(nc2N)C)C)C
InChI
  • InChI=1S/C21H24N4O7S/c1-13(25(12-26)10-16-9-23-14(2)24-20(16)22)18(33-21(29)17-5-4-7-30-17)6-8-31-19(28)11-32-15(3)27/h4-5,7,9,12H,6,8,10-11H2,1-3H3,(H2,22,23,24)/b18-13+ checkY
  • Key:MYBUGVXNAHWTOL-QGOAFFKASA-N checkY
 ☒NcheckY (what is this?)  (verify)

Acefurtiamine (INN) is a vitamin B1 analog in a manner similar to the GABAergic activity of the thiamine derivative clomethiazole.[1] It functions as an analgesic agent at sufficient doses.[medical citation needed]

References

  1. ^ Martindale W (1993). The Extra Pharmacopoeia. Pharmaceutical Press. p. 1053. ISBN 978-0-85369-300-0.

Further reading

  • Elks J, Ganellin CR, eds. (1990). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–. doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2085-3.
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Vitamins (A11)
Fat
soluble
A
D
E
K
  • Naphthoquinone
  • Phylloquinone (K1)#
  • Menaquinones (K2)
  • Menadione (K3)‡
  • Various (K4)
  • 4-Amino-2-methyl-1-naphthol (K5)‡
  • 2-Methylnaphthalene-1,4-diamine (K6)
  • 4-Amino-3-methyl-1-naphthol (K7)
Water
soluble
B
C
Combinations


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