C6orf89

Protein-coding gene in the species Homo sapiens
C6orf89
Identifiers
AliasesC6orf89, BRAP, chromosome 6 open reading frame 89, PS1TP5TP1
External IDsOMIM: 616642; MGI: 2136782; HomoloGene: 12728; GeneCards: C6orf89; OMA:C6orf89 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for C6orf89
Genomic location for C6orf89
Band6p21.2Start36,871,870 bp[1]
End36,928,964 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for C6orf89
Genomic location for C6orf89
Band17|17 A3.3Start29,268,788 bp[2]
End29,314,065 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • myocardium of left ventricle

  • cardiac muscle tissue of right atrium

  • islet of Langerhans

  • tendon of biceps brachii

  • smooth muscle tissue

  • corpus epididymis

  • stromal cell of endometrium

  • internal globus pallidus

  • pars reticulata

  • nipple
Top expressed in
  • retinal pigment epithelium

  • cardiac muscle tissue of left ventricle

  • lacrimal gland

  • right ventricle

  • epithelium of lens

  • right kidney

  • interventricular septum

  • fossa

  • aortic valve

  • left lobe of liver
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integral component of membrane
  • Golgi apparatus
  • Golgi membrane
  • nucleus
  • plasma membrane
  • nucleolus
  • midbody
  • membrane
  • cytoplasm
Biological process
  • positive regulation of histone deacetylase activity
  • epithelial cell proliferation
  • wound healing
  • positive regulation of cell cycle
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

221477

80748

Ensembl

ENSG00000198663

ENSMUSG00000052712

UniProt

Q6UWU4

Q99KU6

RefSeq (mRNA)

NM_001286635
NM_001286636
NM_001286637
NM_152734

NM_030561

RefSeq (protein)

NP_001273564
NP_001273565
NP_001273566
NP_689947
NP_001273564.1

NP_085038

Location (UCSC)Chr 6: 36.87 – 36.93 MbChr 17: 29.27 – 29.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Uncharacterized protein C6orf89 is a protein that in humans is encoded by the C6orf89 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198663 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052712 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: C6orf89 chromosome 6 open reading frame 89".

External links

Further reading

  • Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Zhang JK, Zhao LF, Cheng J, Guo J, Wang DQ, Hong Y, Mao Y (Mar 2007). "Screening and cloning for proteins transactivated by the PS1TP5 protein of hepatitis B virus: a suppression subtractive hybridization study". World Journal of Gastroenterology. 13 (10): 1602–7. doi:10.3748/wjg.v13.i10.1602. PMC 4146906. PMID 17461456.


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