CCDC53

Protein-coding gene in humans
WASHC3
Identifiers
AliasesWASHC3, CGI-116, CCDC53, coiled-coil domain containing 53, WASH complex subunit 3
External IDsMGI: 1914532; HomoloGene: 9364; GeneCards: WASHC3; OMA:WASHC3 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for WASHC3
Genomic location for WASHC3
Band12q23.2Start102,012,840 bp[1]
End102,062,149 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for WASHC3
Genomic location for WASHC3
Band10|10 C1Start88,201,093 bp[2]
End88,246,158 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • Achilles tendon

  • decidua

  • C1 segment

  • sperm

  • tibial arteries

  • left coronary artery

  • Descending thoracic aorta

  • right coronary artery
Top expressed in
  • lens

  • morula

  • epithelium of lens

  • intercostal muscle

  • sternocleidomastoid muscle

  • blastocyst

  • triceps brachii muscle

  • seminiferous tubule

  • belly cord

  • endocardial cushion
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • endosome
  • early endosome
  • WASH complex
Biological process
  • protein transport
  • biological process
  • exocytosis
  • actin filament polymerization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51019

67282

Ensembl

ENSG00000120860

ENSMUSG00000020056

UniProt

Q9Y3C0

Q9CR27

RefSeq (mRNA)

NM_001301107
NM_016053

NM_001122960
NM_026070
NM_027487

RefSeq (protein)

NP_001288036
NP_057137

NP_001116432
NP_080346
NP_081763

Location (UCSC)Chr 12: 102.01 – 102.06 MbChr 10: 88.2 – 88.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

WASH complex subunit 3, formerly known as coiled-coil domain-containing protein 53 (CCDC53), is a protein that in humans is encoded by the WASHC3 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120860 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020056 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. ^ "Entrez Gene: CCDC53 coiled-coil domain containing 53".

External links

Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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