CDC123

Protein-coding gene in the species Homo sapiens
CDC123
Identifiers
AliasesCDC123, C10orf7, D123, cell division cycle 123
External IDsOMIM: 617708; MGI: 2138811; HomoloGene: 4394; GeneCards: CDC123; OMA:CDC123 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for CDC123
Genomic location for CDC123
Band10p14-p13Start12,195,965 bp[1]
End12,250,589 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for CDC123
Genomic location for CDC123
Band2|2 A1Start5,799,105 bp[2]
End5,849,975 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • rectum

  • secondary oocyte

  • islet of Langerhans

  • smooth muscle tissue

  • ventricular zone

  • embryo

  • ganglionic eminence

  • right auricle

  • monocyte

  • mucosa of transverse colon
Top expressed in
  • ventricular zone

  • neural layer of retina

  • medial ganglionic eminence

  • genital tubercle

  • neural tube

  • tail of embryo

  • otic vesicle

  • superior frontal gyrus

  • epiblast

  • mandibular prominence
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8872

98828

Ensembl

ENSG00000151465

ENSMUSG00000039128

UniProt

O75794

Q8CII2

RefSeq (mRNA)

NM_006023

NM_133837
NM_001356501
NM_001356502
NM_001356503
NM_001356504

RefSeq (protein)

NP_006014

NP_598598
NP_001343430
NP_001343431
NP_001343432
NP_001343433

Location (UCSC)Chr 10: 12.2 – 12.25 MbChr 2: 5.8 – 5.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cell division cycle protein 123 homolog is a protein that in humans is encoded by the CDC123 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000151465 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039128 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bieganowski P, Shilinski K, Tsichlis PN, Brenner C (Oct 2004). "Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance". J Biol Chem. 279 (43): 44656–66. doi:10.1074/jbc.M406151200. PMID 15319434.
  6. ^ "Entrez Gene: CDC123 cell division cycle 123 homolog (S. cerevisiae)".

External links

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Okuda A, Kimura G (1996). "An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1". Exp. Cell Res. 223 (2): 242–9. doi:10.1006/excr.1996.0078. PMID 8601400.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Onisto M, Zeilante P, Scannapieco P, et al. (1998). "Expression study on D123 gene product: evidence for high positivity in testis". Exp. Cell Res. 242 (2): 451–9. doi:10.1006/excr.1998.4074. PMID 9683532.
  • Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Exp. Cell Res. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID 10942595.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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