ESCAPPM

ESCAPPM or ESCHAAPPM is a mnemonic for the organisms with inducible beta-lactamase activity that is chromosomally mediated.[1]

  • E: Enterobacter spp.
  • S: Serratia spp.
  • C: Citrobacter freundii
  • H: Hafnia spp.
  • A: Acinetobacter spp.
  • A: Aeromonas spp.
  • P: Proteus spp. (excluding P. mirabilis)
  • P: Providencia spp.
  • M: Morganella morganii

In vitro sensitivities are not applicable in vivo.

In general, treatment with cephalosporins results in induction of AmpC beta-lactamase.[2] Treatment with an aminoglycoside or carbapenem is usually indicated. Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity. They have a structure that renders them highly resistant to beta-lactamases. Examples of carbapenems include meropenem and imipenem.

References

  1. ^ "Feedback for Practical 10: Antimicrobial Agents". Archived from the original on July 23, 2005. Retrieved 2010-01-26.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  2. ^ Philippon, Alain; Arlet, Guillaume; Jacoby, George A. (January 2002). "Plasmid-Determined AmpC-Type β-Lactamases". Antimicrobial Agents and Chemotherapy. 46 (1): 1–11. doi:10.1128/AAC.46.1.1-11.2002. PMC 126993.