HOCPCA

Chemical compound
HOCPCA
Names
Preferred IUPAC name
3-Hydroxycyclopent-1-ene-1-carboxylic acid
Identifiers
CAS Number
  • 867178-11-8 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2431324
ChemSpider
  • 26333262
PubChem CID
  • 21750168
CompTox Dashboard (EPA)
  • DTXSID20617694 Edit this at Wikidata
InChI
  • InChI=1S/C6H8O3/c7-5-2-1-4(3-5)6(8)9/h3,5,7H,1-2H2,(H,8,9)
    Key: VKJGQKRRULDFCI-UHFFFAOYSA-N
  • C1CC(=CC1O)C(=O)O
Properties
Chemical formula
 C6H8O3
Molar mass 128.127 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound

HOCPCA (3-hydroxycyclopent-1-enecarboxylic acid) is a compound with an affinity for the GHB receptor 39 times greater than that of GHB itself.[1]

See also

  • T-HCA

References

  1. ^ Wellendorph P, Høg S, Greenwood JR, de Lichtenberg A, Nielsen B, Frølund B, Brehm L, Clausen RP, Bräuner-Osborne H (2005). "Novel Cyclic γ-Hydroxybutyrate (GHB) Analogs with High Affinity and Stereoselectivity of Binding to GHB Sites in Rat Brain". The Journal of Pharmacology and Experimental Therapeutics. 315 (1): 346–351. doi:10.1124/jpet.105.090472. PMID 16014570.
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GHB receptor modulators
Receptor
(ligands)
GHBRTooltip GHB receptor
GABABTooltip γ-Aminobutyric acid B receptor
  • See here instead.
Transporter
(blockers)
MCTsTooltip Monocarboxylate transporters
SMCTsTooltip Sodium-coupled monocarboxylate transporters
VIATTTooltip Vesicular inhibitory amino acid transporter
Enzyme
(inhibitors)
SSRTooltip Succinic semialdehyde reductase
GHBDHTooltip 4-Hydroxybutyrate dehydrogenase
HOTTooltip Hydroxyacid-oxoacid transhydrogenase
ADHTooltip Alcohol dehydrogenase
ALDHTooltip Aldehyde dehydrogenase
See also
Receptor/signaling modulators
GABA receptor modulators
Glutamate receptor modulators
Glycine receptor modulators


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