MFAP1

Protein-coding gene in the species Homo sapiens
MFAP1
Identifiers
AliasesMFAP1, microfibrillar associated protein 1, microfibril associated protein 1, AMP
External IDsOMIM: 600215; MGI: 1914782; HomoloGene: 4332; GeneCards: MFAP1; OMA:MFAP1 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for MFAP1
Genomic location for MFAP1
Band15q15.3Start43,804,492 bp[1]
End43,824,690 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for MFAP1
Genomic location for MFAP1
Band2|2 E5Start121,322,392 bp[2]
End121,337,146 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • hair follicle

  • gonad

  • ventricular zone

  • cartilage tissue

  • epithelium of nasopharynx

  • amniotic fluid

  • germinal epithelium

  • Achilles tendon

  • right adrenal gland
Top expressed in
  • Rostral migratory stream

  • retinal pigment epithelium

  • ciliary body

  • vas deferens

  • human fetus

  • efferent ductule

  • iris

  • epithelium of lens

  • hand

  • lobe of prostate
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
  • RNA binding
Cellular component
  • microfibril
  • extracellular region
  • nucleus
  • spliceosomal complex
  • U2-type precatalytic spliceosome
Biological process
  • biological process
  • mRNA splicing, via spliceosome
  • mRNA processing
  • RNA splicing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

4236

67532

Ensembl

ENSG00000140259

ENSMUSG00000068479

UniProt

P55081

C0HKD8
C0HKD9

RefSeq (mRNA)

NM_005926

NM_026220

RefSeq (protein)

NP_005917

NP_001075444
NP_080496

Location (UCSC)Chr 15: 43.8 – 43.82 MbChr 2: 121.32 – 121.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Microfibrillar-associated protein 1 is a protein that in humans is encoded by the MFAP1 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140259 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068479 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yeh H, Chow M, Abrams WR, Fan J, Foster J, Mitchell H, Muenke M, Rosenbloom J (Feb 1995). "Structure of the human gene encoding the associated microfibrillar protein (MFAP1) and localization to chromosome 15q15-q21". Genomics. 23 (2): 443–9. doi:10.1006/geno.1994.1521. PMID 7835894.
  6. ^ "Entrez Gene: MFAP1 microfibrillar-associated protein 1".

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. CiteSeerX 10.1.1.323.5263. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Weinmann AS, Yan PS, Oberley MJ, et al. (2002). "Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis". Genes Dev. 16 (2): 235–44. doi:10.1101/gad.943102. PMC 155318. PMID 11799066.


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