Meglutol
Chemical compound
- C10AX05 (WHO)
- 3-hydroxy-3-methylpentanedioic acid
- 503-49-1
N
- 1662
- DB04377
Y
- 1600 Y
- CLA99KCD53
- D04897 Y
- CHEBI:16831 Y
- ChEMBL50444 Y
- DTXSID90198304
- Interactive image
- O=C(O)CC(O)(C)CC(=O)O
InChI
- InChI=1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)Y
- Key:NPOAOTPXWNWTSH-UHFFFAOYSA-NY
N
Y (what is this?) (verify)Meglutol (INN, also known as 3-hydroxy-3-methylglutaric acid, β-hydroxy-β-methylglutaric acid, and dicrotalic acid) is a hypolipidemic agent.
It occurs free in Crotalaria dura and C. globifera and is bound in dicrotaline (pyrrolizidine alkaloid).
See also
- Crotalaria
- List of Crotalaria species
- Mevalonic acid
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| Cholesterol absorption inhibitors, NPC1L1 | |
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| Bile acid sequestrants/resins (LDL) |
| Statins (HMG-CoA reductase, LDL) | |
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| Niacin and derivatives (HDL and LDL) | |
| MTTP inhibitors (VLDL) | |
| ATP citrate lyase inhibitors (LDL) | |
| Thyromimetics (VLDL) |
| PPAR agonists (LDL) |
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| CETP inhibitors (HDL) | |||||
| PCSK9 inhibitors (LDL) | |||||
| ANGPTL3 inhibitors (LDL/HDL) |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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