NLGN2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | NLGN2, neuroligin 2 |
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External IDs | OMIM: 606479; MGI: 2681835; HomoloGene: 69317; GeneCards: NLGN2; OMA:NLGN2 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17p13.1 | Start | 7,404,874 bp[1] |
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End | 7,419,860 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B3 | Start | 69,713,948 bp[2] |
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End | 69,728,610 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right hemisphere of cerebellum
- superior frontal gyrus
- right ovary
- primary visual cortex
- ganglionic eminence
- body of uterus
- right frontal lobe
- stromal cell of endometrium
- left ovary
- nucleus accumbens
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| Top expressed in | - subiculum
- dorsomedial hypothalamic nucleus
- piriform cortex
- superior colliculus
- anterior amygdaloid area
- primary visual cortex
- internal carotid artery
- superior frontal gyrus
- cerebellar cortex
- cerebellar vermis
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - carboxylic ester hydrolase activity
- neurexin family protein binding
- cell adhesion molecule binding
- signaling receptor activity
- identical protein binding
| Cellular component | - integral component of membrane
- postsynaptic membrane
- membrane
- synapse
- inhibitory synapse
- cell surface
- cell junction
- presynaptic membrane
- plasma membrane
- integral component of plasma membrane
- integral component of postsynaptic membrane
- intracellular anatomical structure
- spanning component of membrane
- glycinergic synapse
- dopaminergic synapse
- GABA-ergic synapse
- symmetric, GABA-ergic, inhibitory synapse
- integral component of postsynaptic specialization membrane
| Biological process | - neuromuscular process controlling balance
- neuron cell-cell adhesion
- positive regulation of inhibitory postsynaptic potential
- synapse organization
- modulation of chemical synaptic transmission
- positive regulation of protein localization to synapse
- gephyrin clustering involved in postsynaptic density assembly
- postsynaptic density protein 95 clustering
- positive regulation of synaptic transmission, GABAergic
- regulation of AMPA receptor activity
- locomotory exploration behavior
- regulation of respiratory gaseous exchange by nervous system process
- cell-cell junction maintenance
- positive regulation of synaptic vesicle clustering
- positive regulation of synaptic transmission, glutamatergic
- cell adhesion
- positive regulation of excitatory postsynaptic potential
- sensory perception of pain
- terminal button organization
- protein localization to synapse
- positive regulation of insulin secretion
- positive regulation of synapse assembly
- inhibitory synapse assembly
- synapse assembly
- synaptic vesicle endocytosis
- postsynaptic membrane assembly
- presynaptic membrane assembly
- cell-cell adhesion
- postsynaptic specialization assembly
- presynapse assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000169992 ENSG00000283859 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 17: 7.4 – 7.42 Mb | Chr 11: 69.71 – 69.73 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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