SERF2

Protein-coding gene in the species Homo sapiens
SERF2
Identifiers
AliasesSERF2, 4F5REL, FAM2C, H4F5REL, HsT17089, small EDRK-rich factor 2
External IDsOMIM: 605054; MGI: 1337041; HomoloGene: 85994; GeneCards: SERF2; OMA:SERF2 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for SERF2
Genomic location for SERF2
Band15q15.3Start43,777,087 bp[1]
End43,804,427 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for SERF2
Genomic location for SERF2
Band2|2 E5Start121,279,676 bp[2]
End121,288,794 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • stromal cell of endometrium

  • left adrenal gland

  • right lobe of thyroid gland

  • prostate

  • left lobe of thyroid gland

  • kidney

  • placenta

  • anterior pituitary

  • thoracic aorta

  • ascending aorta
Top expressed in
  • white adipose tissue

  • quadriceps femoris muscle

  • duodenum

  • urinary bladder

  • adrenal gland

  • heart

  • lens

  • jejunum

  • pancreas

  • blastocyst
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • molecular function
Cellular component
  • cytosol
  • nucleus
Biological process
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10169

378702

Ensembl

ENSG00000140264

ENSMUSG00000074884

UniProt

P84101

P84102

RefSeq (mRNA)
NM_001018108
NM_001199875
NM_001199876
NM_001199877
NM_001199878

NM_005770

NM_001290837
NM_011354

RefSeq (protein)

NP_001018118
NP_001186804
NP_001186805
NP_001186806
NP_001186807

NP_001277766
NP_035484

Location (UCSC)Chr 15: 43.78 – 43.8 MbChr 2: 121.28 – 121.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Small EDRK-rich factor 2 is a protein that in humans is encoded by the SERF2 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140264 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074884 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Scharf JM, Endrizzi MG, Wetter A, Huang S, Thompson TG, Zerres K, Dietrich WF, Wirth B, Kunkel LM (September 1998). "Identification of a candidate modifying gene for spinal muscular atrophy by comparative genomics". Nature Genetics. 20 (1): 83–6. doi:10.1038/1753. PMID 9731538. S2CID 33032570.
  6. ^ "Entrez Gene: SERF2 small EDRK-rich factor 2".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (September 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.
  • Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (October 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  • Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y (August 2006). "Substrate and functional diversity of lysine acetylation revealed by a proteomics survey". Molecular Cell. 23 (4): 607–18. doi:10.1016/j.molcel.2006.06.026. PMID 16916647.

External links

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