SNAPC5

Protein-coding gene in the species Homo sapiens
SNAPC5
Identifiers
AliasesSNAPC5, SNAP19, small nuclear RNA activating complex polypeptide 5
External IDsOMIM: 605979; MGI: 1914282; HomoloGene: 4414; GeneCards: SNAPC5; OMA:SNAPC5 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for SNAPC5
Genomic location for SNAPC5
Band15q22.31Start66,490,135 bp[1]
End66,497,780 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for SNAPC5
Genomic location for SNAPC5
Band9|9 CStart64,086,556 bp[2]
End64,090,414 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endothelial cell

  • middle temporal gyrus

  • sperm

  • Brodmann area 23

  • palpebral conjunctiva

  • gastrocnemius muscle

  • vastus lateralis muscle

  • prefrontal cortex

  • biceps brachii

  • corpus epididymis
Top expressed in
  • interventricular septum

  • morula

  • yolk sac

  • esophagus

  • superior cervical ganglion

  • blastocyst

  • lip

  • urethra

  • visual cortex

  • female urethra
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • protein binding
Cellular component
  • nucleolus
  • nucleus
  • nucleoplasm
  • nuclear body
Biological process
  • regulation of transcription, DNA-templated
  • transcription by RNA polymerase II
  • transcription initiation from RNA polymerase III promoter
  • transcription, DNA-templated
  • snRNA transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10302

330959

Ensembl

ENSG00000174446

ENSMUSG00000032398

UniProt

O75971

Q8R2K7

RefSeq (mRNA)

NM_001329613
NM_001329614
NM_001329615
NM_006049

NM_183316
NM_025925

RefSeq (protein)

NP_001316542
NP_001316543
NP_001316544
NP_006040

NP_899139

Location (UCSC)Chr 15: 66.49 – 66.5 MbChr 9: 64.09 – 64.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

snRNA-activating protein complex subunit 5 is a protein that in humans is encoded by the SNAPC5 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174446 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032398 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Henry RW, Mittal V, Ma B, Kobayashi R, Hernandez N (Oct 1998). "SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III". Genes Dev. 12 (17): 2664–72. doi:10.1101/gad.12.17.2664. PMC 317148. PMID 9732265.
  6. ^ "Entrez Gene: SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ma B, Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. PMID 11056176.

External links


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