Serotonin–norepinephrine releasing agent
Drug class
![](http://upload.wikimedia.org/wikipedia/commons/thumb/3/3e/MBDB.svg/200px-MBDB.svg.png)
![](http://upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Norfenfluramine.png/200px-Norfenfluramine.png)
A serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain.
Only a few SNRAs are known, examples of which include norfenfluramine and MBDB. Fenfluramine/phentermine (Fen-Phen), a combination formulation of fenfluramine, a serotonin releasing agent, and phentermine, a norepinephrine releasing agent, is a functional SNRA that was formerly used as an appetite suppressant for the treatment of obesity.
A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor (SNRI).
See also
- Monoamine releasing agent
- Serotonin releasing agent
- Norepinephrine releasing agent
- Serotonin–dopamine releasing agent
- Serotonin–norepinephrine–dopamine releasing agent
References
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- DAT modulators: Agonist-like: SoRI-9804
- SoRI-20040; Antagonist-like: SoRI-20041
- Adrenergic release blockers: Bethanidine
- Bretylium
- Guanadrel
- Guanazodine
- Guanethidine
- Guanoxan
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins
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