ZNF277P

Protein-coding gene in the species Homo sapiens
ZNF277
Identifiers
AliasesZNF277, NRIF4, ZNF277P, zinc finger protein 277
External IDsOMIM: 605465; MGI: 1890393; HomoloGene: 11087; GeneCards: ZNF277; OMA:ZNF277 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ZNF277
Genomic location for ZNF277
Band7q31.1Start112,206,695 bp[1]
End112,343,934 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for ZNF277
Genomic location for ZNF277
Band12|12 B1Start40,365,045 bp[2]
End40,495,901 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • monocyte

  • germinal epithelium

  • islet of Langerhans

  • body of pancreas

  • ganglionic eminence

  • jejunal mucosa

  • oocyte

  • skin of thigh

  • gallbladder
Top expressed in
  • primary oocyte

  • cumulus cell

  • efferent ductule

  • vas deferens

  • abdominal wall

  • medial ganglionic eminence

  • zygote

  • secondary oocyte

  • ovary

  • endocardial cushion
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • RNA polymerase II cis-regulatory region sequence-specific DNA binding
  • RNA polymerase II core promoter sequence-specific DNA binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
Biological process
  • regulation of cellular senescence
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • cellular response to hydrogen peroxide
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11179

246196

Ensembl

ENSG00000198839

ENSMUSG00000055917

UniProt

Q9NRM2

E9Q6D6

RefSeq (mRNA)

NM_021994

NM_172575
NM_178845

RefSeq (protein)

NP_068834

NP_766163
NP_849173

Location (UCSC)Chr 7: 112.21 – 112.34 MbChr 12: 40.37 – 40.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 277 is a protein that in humans is encoded by the ZNF277 gene.[5][6][7][8]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198839 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055917 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Liang H, Guo W, Nagarajan L (Aug 2000). "Chromosomal mapping and genomic organization of an evolutionarily conserved zinc finger gene ZNF277". Genomics. 66 (2): 226–8. doi:10.1006/geno.2000.6198. PMID 10860669.
  6. ^ Liang H, Castro PD, Ma J, Nagarajan L (Oct 2005). "Finer delineation and transcript map of the 7q31 locus deleted in myeloid neoplasms". Cancer Genet Cytogenet. 162 (2): 151–9. doi:10.1016/j.cancergencyto.2005.03.019. PMID 16213364.
  7. ^ Hahn Y, Lee B (Feb 2006). "Human-specific nonsense mutations identified by genome sequence comparisons". Hum Genet. 119 (1–2): 169–78. doi:10.1007/s00439-005-0125-6. PMID 16395595. S2CID 21059468.
  8. ^ "Entrez Gene: ZNF277P zinc finger protein 277 pseudogene".

Further reading

  • Kumar S; Connor JR; Dodds RA; et al. (2001). "Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries". Osteoarthr. Cartil. 9 (7): 641–53. doi:10.1053/joca.2001.0421. PMID 11597177.
  • Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Scherer SW; Cheung J; MacDonald JR; et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Hillier LW; Fulton RS; Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
  • Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Lim J; Hao T; Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
  • Ewing RM; Chu P; Elisma F; et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.


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