Молекулярна функція | • protein homodimerization activity • protein heterodimerization activity • RNA polymerase II transcription regulatory region sequence-specific DNA binding • зв'язування з іоном металу • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • sequence-specific DNA binding • GO:0001158 cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • I-SMAD binding • collagen binding • GO:0001948, GO:0016582 protein binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • R-SMAD binding • identical protein binding • sulfate binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001104 transcription coregulator activity • molecular function regulator • chromatin binding |
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Біологічний процес | • negative regulation of cell population proliferation • Сперматогенез • positive regulation of pathway-restricted SMAD protein phosphorylation • positive regulation of luteinizing hormone secretion • regulation of cell population proliferation • cardiac septum development • negative regulation of cell death • regulation of hair follicle development • cellular response to BMP stimulus • epithelial to mesenchymal transition involved in endocardial cushion formation • brainstem development • проліферація • regulation of binding • SMAD protein complex assembly • metanephric mesenchyme morphogenesis • positive regulation of epithelial to mesenchymal transition • GO:0007329 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • branching involved in ureteric bud morphogenesis • GO:0009373 regulation of transcription, DNA-templated • embryonic digit morphogenesis • uterus development • axon guidance • somatic stem cell population maintenance • гаструляція • positive regulation of histone H3-K4 methylation • GO:0045996 negative regulation of transcription, DNA-templated • response to transforming growth factor beta • endothelial cell activation • positive regulation of transforming growth factor beta receptor signaling pathway • single fertilization • transforming growth factor beta receptor signaling pathway • anterior/posterior pattern specification • in utero embryonic development • positive regulation of cell proliferation involved in heart valve morphogenesis • atrioventricular valve formation • GO:0007243 intracellular signal transduction • developmental growth • endoderm development • cellular iron ion homeostasis • розвиток нирки • GO:0007364, GO:0007361, GO:0007358 formation of anatomical boundary • positive regulation of histone H3-K9 acetylation • regulation of transforming growth factor beta2 production • interleukin-6-mediated signaling pathway • GO:1901227 negative regulation of transcription by RNA polymerase II • male gonad development • ovarian follicle development • endocardial cell differentiation • nephrogenic mesenchyme morphogenesis • gastrulation with mouth forming second • female gonad development • SMAD protein signal transduction • response to hypoxia • atrioventricular canal development • mesoderm development • negative regulation of cell growth • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • BMP signaling pathway • tissue morphogenesis • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of SMAD protein signal transduction • somite rostral/caudal axis specification • sebaceous gland development • positive regulation of follicle-stimulating hormone secretion • positive regulation of BMP signaling pathway • neural crest cell differentiation • seminiferous tubule development • female gonad morphogenesis • regulation of transforming growth factor beta receptor signaling pathway • neuron fate commitment • transcription, DNA-templated • outflow tract septum morphogenesis • left ventricular cardiac muscle tissue morphogenesis • negative regulation of cardiac muscle hypertrophy • protein deubiquitination • ventricular septum morphogenesis • negative regulation of ERK1 and ERK2 cascade • negative regulation of cardiac myofibril assembly • protein homotrimerization • pri-miRNA transcription by RNA polymerase II • secondary palate development • anatomical structure morphogenesis • диференціація клітин • mesendoderm development |
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