Ciclobendazole

Chemical compound
  • P02CA04 (WHO)
Identifiers
  • Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
CAS Number
  • 31431-43-3 checkY
PubChem CID
  • 35803
ChemSpider
  • 32933 ☒N
UNII
  • JF3KQ40J31
KEGG
  • D03623 checkY
CompTox Dashboard (EPA)
  • DTXSID9057713 Edit this at Wikidata
ECHA InfoCard100.046.018 Edit this at WikidataChemical and physical dataFormulaC13H13N3O3Molar mass259.265 g·mol−13D model (JSmol)
  • Interactive image
  • COC(=O)Nc3nc2ccc(C(=O)C1CC1)cc2[nH]3
InChI
  • InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18) ☒N
  • Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis.[1]

It is not known to be marketed anywhere in the world.[2]

References

  1. ^ Guggenmoos R, Akhtaruzzaman KM, Rosenkaimer F, Gaus W, Bienzle U, Dietrich M (December 1978). "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und Parasitologie. 29 (4): 423–6. PMID 369076.
  2. ^ "Ciclobendazole search results". Drugs.com. Retrieved 2021-03-31.
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Antiplatyhelmintic agents
Antitrematodals
(schistosomicides)
Binds tubulin
AChE inhibitor
Other/unknown
Anticestodals
(taeniacides)
Binds tubulin
Other/unknown
Antinematodal agents
(including
macrofilaricides)
Binds tubulin
Glutamate-gated chloride channel, GABA receptor
NMDA
Other/unknown
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