Desaspidin

Chemical compound

P02DX01 (WHO)

Identifiers

IUPAC name

2-Butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxyphenyl)methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one

CAS Number

114-43-2^Y

PubChem CID

8238

ChemSpider

10295071^N

UNII

KV3495SGKS

KEGG

D07365^Y

ChEMBL

ChEMBL2105606^N

CompTox Dashboard (EPA)

DTXSID00976317 DTXSID6074461, DTXSID00976317

ECHA InfoCard100.003.680

Chemical and physical dataFormulaC₂₄H₃₀O₈Molar mass446.496 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

CCCC(=O)C1=C(C(=C(C=C1O)OC)CC2=C(C(C(=C(C2=O)C(=O)CCC)O)(C)C)O)O

InChI

InChI=1S/C24H30O8/c1-6-8-14(25)18-16(27)11-17(32-5)12(20(18)28)10-13-21(29)19(15(26)9-7-2)23(31)24(3,4)22(13)30/h11,27-28,30-31H,6-10H2,1-5H3^N
Key:GAHOBHHMYUYJDT-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Desaspidin is an anthelmintic. Desapidin may occur in natural form within some plants such as Coastal woodfern, Dryopteris arguta.^[1] Since the 1950s the inhibition effects of desapidins upon phosphorylation in chloroplasts has been noted and studied.^[2]

References

^ Hogan CM (2008). Stromberg M (ed.). "Coastal Woodfern (Dryopteris arguta)". GlobalTwitcher. Archived from the original on 2011-07-11.
^ Bacon K (2001). Photosynthesis : photobiochemistry and photobiophysics. Dordrecht: Kluwer Academic Publishers. ISBN 0-7923-6791-X.

Antiparasitics – Anthelmintics (P02) and endectocides (QP54)

Antiplatyhelmintic agents

Antitrematodals
(schistosomicides)

Binds tubulin	benzimidazole Triclabendazole^#
AChE inhibitor	phosphonic acid Metrifonate^‡
Other/unknown	quinoline Arpraziquantel Praziquantel^# Oxamniquine^# phenol Bithionol thiazole Niridazole thioxanthone Hycanthone Lucanthone antimony compounds Stibophen Tartar emetic^‡

Anticestodals
(taeniacides)

Binds tubulin	benzimidazole Albendazole^#
Other/unknown	quinoline Praziquantel^# salicylanilide Niclosamide^# aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Antinematodal agents
(including
macrofilaricides)

Binds tubulin	benzimidazole Mebendazole^# Albendazole^# Tiabendazole Fenbendazole Ciclobendazole Flubendazole
Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Eprinomectin Ivermectin^# Selamectin milbemycins Moxidectin Milbemycin oxime
NMDA	tetrahydropyrimidine Pyrantel^# pyrantel pamoate Oxantel Morantel Carbantel Febantel (aka felsantel)
Other/unknown	piperazine Piperazine Diethylcarbamazine^# thiazole Levamisole^# quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin^# Ascaridole^‡ Hexylresorcinol Santonin^‡ Tribendimidine Tetrachloroethylene^‡