EDA2R |
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Identifiers |
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Aliases | EDA2R, EDA-A2R, EDAA2R, TNFRSF27, XEDAR, ectodysplasin A2 receptor |
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External IDs | OMIM: 300276; MGI: 2442860; HomoloGene: 11033; GeneCards: EDA2R; OMA:EDA2R - orthologs |
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Gene location (Human) |
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| Chr. | X chromosome (human)[1] |
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| Band | Xq12 | Start | 66,595,637 bp[1] |
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End | 66,639,298 bp[1] |
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Gene location (Mouse) |
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| Chr. | X chromosome (mouse)[2] |
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| Band | X|X C3 | Start | 96,377,446 bp[2] |
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End | 96,420,822 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - stromal cell of endometrium
- right adrenal cortex
- right uterine tube
- Descending thoracic aorta
- ascending aorta
- testicle
- smooth muscle tissue
- left adrenal gland
- canal of the cervix
- left adrenal cortex
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| Top expressed in | - temporal muscle
- ankle
- gastrocnemius muscle
- endothelial cell of lymphatic vessel
- triceps brachii muscle
- muscle of thigh
- quadriceps femoris muscle
- soleus muscle
- medial head of gastrocnemius muscle
- tibialis anterior muscle
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- tumor necrosis factor-activated receptor activity
- signaling receptor activity
| Cellular component | - integral component of membrane
- integral component of plasma membrane
- intracellular anatomical structure
- membrane
- plasma membrane
| Biological process | - multicellular organism development
- cell differentiation
- tumor necrosis factor-mediated signaling pathway
- positive regulation of JNK cascade
- positive regulation of NF-kappaB transcription factor activity
- ectodermal cell differentiation
- intrinsic apoptotic signaling pathway by p53 class mediator
- epidermis development
- tissue development
- positive regulation of I-kappaB kinase/NF-kappaB signaling
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001199687 NM_001199688 NM_001199689 NM_001242310 NM_021783
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NM_001324199 NM_001324201 NM_001324202 NM_001324204 NM_001324205 NM_001324206 |
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NM_001161432 NM_001161433 NM_175540 |
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RefSeq (protein) | NP_001186616 NP_001229239 NP_001311128 NP_001311130 NP_001311131
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NP_001311133 NP_001311134 NP_001311135 NP_068555 |
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NP_001154904 NP_001154905 NP_780749 |
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Location (UCSC) | Chr X: 66.6 – 66.64 Mb | Chr X: 96.38 – 96.42 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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