Kalsitonin |
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Struktur sedia ada |
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PDB | Pencarian ortolog: PDBe RCSB |
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Senarai kod PDB |
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2JXZ,%%s1LS7 |
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Pengecam |
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Alias | CALCA, CT, CGRP-I, CGRP-alpha, KC, PCT, calcitonin related polypeptide alpha, CGRP, CGRP1, CALC1 |
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Pengecam-pengecam luaran | OMIM: 114130 MGI: 2151253 HomoloGene: 88401 GeneCards: CALCA |
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Kedudukan gen (Manusia) |
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| Kr. | Kromosom 11[1] |
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| Jalur | 11p15.2 | Mula | 14,966,668 bp[1] |
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Tamat | 14,972,351 bp[1] |
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Corak ekspresi RNA |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Ganglion akar dorsal
- trigeminal ganglion
- buah pinggang
- quadriceps femoris muscle
- vastus lateralis muscle
- cerebellar vermis
- Kelenjar pankreas
- tibialis anterior muscle
- right lobe of liver
- left lobe of thyroid gland
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| Top expressed in | - facial motor nucleus
- motor neuron
- anterior horn of spinal cord
- merih
- trigeminal ganglion
- substantia nigra
- Atrium jantung
- medial geniculate nucleus
- endocardial cushion
- Kelenjar pineal
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| More reference expression data |
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BioGPS |
| Rujukan lanjutan untuk data ekspresi |
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Ontologi gen |
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Fungsi molekul | - hormone activity
- calcitonin receptor binding
- Pengikatan protein plasma
- identical protein binding
- signaling receptor binding
- protein-containing complex binding
| Komponen sel | - Sitoplasma
- Intrasel
- extracellular region
- akson
- terminal bouton
- neuronal cell body
- neuron projection
- nukleus sel
- Ekstrasel
| Proses biologi | - cellular response to nerve growth factor stimulus
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
- negative regulation of smooth muscle contraction
- regulation of heart contraction
- monocyte chemotaxis
- negative regulation of blood pressure
- positive regulation of cytosolic calcium ion concentration
- cellular response to tumor necrosis factor
- penuaan
- vasodilation
- cellular calcium ion homeostasis
- response to heat
- negative regulation of nervous system process
- positive regulation of ossification
- activation of adenylate cyclase activity
- regulation of heart rate
- detection of temperature stimulus involved in sensory perception of pain
- negative regulation of ossification
- response to pain
- artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
- feeding behavior
- inflammatory response
- neuropeptide signaling pathway
- negative regulation of transcription, DNA-templated
- activation of protein kinase activity
- embryo implantation
- negative regulation of bone resorption
- regulation of signaling receptor activity
- G protein-coupled receptor signaling pathway
- adenylate cyclase-activating G protein-coupled receptor signaling pathway
- regulation of cytosolic calcium ion concentration
- leukocyte cell-cell adhesion
- G protein-coupled receptor internalization
- positive regulation of interleukin-1 alpha production
- response to yeast
- negative regulation of osteoclast differentiation
- cell-cell signaling
- antibacterial humoral response
- positive regulation of macrophage differentiation
- receptor internalization
- regulation of blood pressure
- protein phosphorylation
- vasculature development
- defense response to Gram-negative bacterium
- endothelial cell proliferation
- positive regulation of interleukin-8 production
- nervous system process involved in regulation of systemic arterial blood pressure
- negative regulation of calcium ion transport into cytosol
- Sistem imun semula jadi
- endothelial cell migration
- antifungal humoral response
- defense response to Gram-positive bacterium
- antimicrobial humoral immune response mediated by antimicrobial peptide
- amylin receptor signaling pathway
- calcitonin gene-related peptide receptor signaling pathway
| Sumber:Amigo / QuickGO |
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Ortolog |
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Spesies | Manusia | Mencit |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001033952 NM_001033953 NM_001741 NM_001378949 NM_001378950 |
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NM_001033954 NM_007587 NM_001289444 NM_001305616 |
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RefSeq (protein) | | NP_001029126 NP_001276373 NP_001292545 NP_031613 NP_001029126.1
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NP_001276373.1 |
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Kedudukan (UCSC) | Chr 11: 14.97 – 14.97 Mb | tiada data |
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Carian PubMed | [2] | [3] |
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Wikidata |
Papar/Sunting data manusia | Papar/Sunting data mencit |
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