Letolizumab

Monoclonal antibody
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IdentifiersCAS Number
  • 1450981-87-9
ChemSpider
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UNII
  • 449MIE2SD6
KEGG
  • D11122
Chemical and physical dataFormulaC1734H2688N466O538S10Molar mass38991.90 g·mol−1

Letolizumab (INN;[1] development code BMS-986004) is a humanized monoclonal antibody designed for the treatment of inflammatory diseases.[2]

This drug was developed by Bristol-Myers Squibb.[3]

References

  1. ^ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 116" (PDF). WHO Drug Information. 30 (4).
  2. ^ Budamakuntla L, Shree-Lakshmi HV, Bansal A, Venkatarayaraju SK (2019). "Spotlight on itolizumab in the treatment of psoriasis - current perspectives from India". Psoriasis: Targets and Therapy. 9: 19–27. doi:10.2147/PTT.S154073. PMC 6501705. PMID 31119094.
  3. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Letolizumab, American Medical Association.
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Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse
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