Oleclumab

Monoclonal antibody
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IdentifiersCAS Number
  • 1803176-05-7
ChemSpider
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UNII
  • 5CRY01URYQ
KEGG
  • D10963
Chemical and physical dataFormulaC6348H9826N1710O1998S40Molar mass143350.81 g·mol−1

Oleclumab (INN;[1] development code MEDI9447) is a human monoclonal antibody targeting the ectonucleotidase CD73 that was designed for the treatment of pancreatic and colorectal and other cancers.[2]

This drug was developed by MedImmune/AstraZeneca.[3]

References

  1. ^ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 116" (PDF). WHO Drug Information. 30 (4).
  2. ^ ClinicalTrial.gov for Oleclumab
  3. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Oleclumab, American Medical Association.
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Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse